We are a computational genetics lab investigating genetic risk factors within and across diverse human populations.

We are part of the Center for Genetic Epidemiology and the Biostatistics division in the Department of Preventive Medicine at USC Keck School of Medicine. Our research aims to develop novel computational and statistical approaches to understand the genetic etiology of complex diseases. This includes integrating molecular phenotypes (e.g., gene expression, protein abundance) with large-scale genome-wide association studies, characterizing the genetic architecture of complex disease (e.g., rare vs common variation), and quantifying the role of selection in shaping the effect-size distribution for alleles.